Doctor explains Zopiclone (Imovane) | Uses, doses, side effects and more

Zopiclone, commonly known by its brand names Zimovane and Imovane, is a medication that falls under the category of sedative-hypnotics. It is primarily prescribed for the short-term treatment of severe insomnia, a condition characterized by difficulty falling asleep or staying asleep. In this article, I will delve into the essential aspects of zopiclone, including its mechanism of action, usage guidelines, potential side effects, and important precautions to consider.

Understanding Zopiclone

Zopiclone works by enhancing the effects of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA). GABA is a calming chemical that helps to reduce neuronal excitability, leading to a sedative effect. This mechanism is what makes zopiclone effective in helping individuals fall asleep more quickly and reducing nighttime awakenings.

Zopiclone is available in tablet form, with dosages of 3.75 mg and 7.5 mg, as well as in a liquid formulation for those who have difficulty swallowing pills. In the UK, zopiclone is only available via prescription, emphasizing the importance of consulting with a healthcare provider before starting this medication.

Who Should Take Zopiclone?

While zopiclone can be beneficial for many adults over the age of 18, it is not suitable for everyone. It is crucial to inform your doctor if you have any of the following conditions:

• Allergic Reactions: A history of allergic reactions to zopiclone or similar medications.
• Liver or Kidney Issues: Impaired liver or kidney function can affect how the body processes the medication.
• Myasthenia Gravis: This condition causes muscle weakness and may be exacerbated by zopiclone.
• Respiratory Problems: Conditions like sleep apnea, where breathing stops intermittently during sleep, can be worsened by sedative medications.
• Mental Health Concerns: A history of mental health issues, including depression or substance abuse, should be discussed with your doctor.
• Pregnancy and Breastfeeding: Zopiclone is generally not recommended during pregnancy or while breastfeeding.

How to Take Zopiclone

It is essential to follow your healthcare provider's instructions when taking zopiclone. Typically, it is prescribed for short-term use, usually not exceeding 2 to 4 weeks, to minimize the risk of dependence. The standard dosage is one 7.5 mg tablet taken just before bedtime. For older adults or those with liver or kidney problems, a lower dose of 3.75 mg may be recommended to reduce the risk of excessive sedation.

Zopiclone usually takes about an hour to take effect, so it is important to allow sufficient time for the medication to work before attempting to sleep. Patients should swallow the tablet whole and avoid crushing or chewing it, as this can alter its effectiveness.

Potential Side Effects

Like all medications, zopiclone can cause side effects. Common side effects include:

• Metallic or Bitter Taste: Some individuals report an unpleasant taste in their mouth.
• Dry Mouth: This can be bothersome but is generally manageable.
• Daytime Drowsiness: Some users may feel excessively sleepy the following day, which can impact daily activities.

Serious side effects are rare but can occur. If you experience symptoms such as memory problems, hallucinations, delusions, or severe mood changes, it is crucial to contact your healthcare provider immediately. Anaphylaxis, a severe allergic reaction, is also a possibility, and emergency medical attention should be sought if symptoms arise.

Drug Interactions and Precautions

Zopiclone can interact with various medications, increasing the risk of side effects, particularly excessive drowsiness. It is vital to discuss all medications you are currently taking with your doctor, especially:

• Antidepressants and Antipsychotics: These can enhance the sedative effects of zopiclone.
• Antiepileptics: Medications for epilepsy may interact negatively.
• Sedating Antihistamines: Common allergy medications can increase drowsiness.
• Strong Painkillers: Opioids and other potent analgesics can compound the sedative effects.

Emergency Information

Overdosing on zopiclone can lead to severe consequences, including profound drowsiness, confusion, and even coma. Symptoms of overdose may include dizziness, shallow breathing, and loss of balance. If you suspect an overdose, seek immediate medical attention.

Frequently Asked Questions

1. Can I drink alcohol while taking zopiclone?
   • No, alcohol should be avoided as it can significantly enhance the sedative effects, leading to dangerous respiratory depression.
2. Can I drive or operate machinery while on zopiclone?
   • It is advised not to drive or operate heavy machinery if you experience drowsiness, blurred vision, or dizziness after taking zopiclone.

For more detailed information about zopiclone, including its effects on pregnancy, breastfeeding, and long-term use considerations, please refer to the links provided in the video description. Always consult your healthcare provider for personalized advice and guidance regarding your health and medication management.

Please note this is a general educational resource only - and not individual clinical advice. For all individual clinical questions always speak to your own healthcare provider. ALWAYS read the full information leaflet inside the packet.